- St. Paul is a city located in the state of Minnesota, in the United States. It is the capital city of Minnesota and is the second most populous city in the state, after Minneapolis. St. Paul is known for its historical and cultural attractions, including the Cathedral of Saint Paul, the State Capitol building, and the Science Museum of Minnesota. The city is also home to several colleges and universities, including the University of St. Thomas and Hamline University. St. Paul has a vibrant arts and music scene, with numerous theaters, galleries, and music venues. The city is also known for its parks and outdoor recreational opportunities, with many hiking and biking trails, as well as the Mississippi River running through the city.