Santa Ana is a city located in Southern California in Orange County. It is the second largest city in Orange County and the 57th most populous city in the United States. Santa Ana has a population of approximately 330,000 people. The city is known for its diverse population, vibrant arts scene, and historic buildings. Santa Ana is also the county seat of Orange County and is home to several government institutions, including the Ronald Reagan Federal Building and Courthouse. The city has a Mediterranean climate with mild, wet winters and warm, dry summers. Santa Ana is also commonly referred to as the "Downtown Area" of Orange County and is located adjacent to other popular cities such as Irvine and Anaheim.