- Salina City is a city located in Saline County, Kansas, United States. It is the county seat and largest city in Saline County. The city is situated in the center of the state, approximately 81 miles west of Topeka and 179 miles west of Kansas City. Salina City has a population of around 47,000 people, making it the seventh-largest city in Kansas. The city has a rich history in agriculture and is known for its vibrant downtown area, cultural attractions, and outdoor recreational opportunities. Salina City is also home to several educational institutions and has a diverse economy with a mix of industries, including manufacturing, healthcare, and education.