Napakiak is a city located in the Bethel Census Area in the state of Alaska, United States. It is an Alaskan Native village that is primarily inhabited by Yupik Eskimos. The city is situated on the banks of the Kuskokwim River and has a population of approximately 400 people. The economy of Napakiak is largely dependent on subsistence hunting, fishing, and gathering, as well as services provided by the local school and health clinic. The city is accessible primarily by boat or small aircraft, and there are no major roads connecting it to other towns or cities in the region.