Manistee City is a city located in Manistee County, Michigan, United States. It is situated on the Manistee River near the eastern shore of Lake Michigan. Manistee City has a population of approximately 6,226 people as of the 2010 United States Census. The city is known for its historic downtown district, Victorian-era architecture, and beautiful natural surroundings. It is a popular tourist destination, offering opportunities for outdoor activities such as fishing, boating, and hiking. Manistee City also has a vibrant arts and cultural scene, with numerous galleries, theaters, and music venues.