- Eugene is a city located in the state of Oregon in the United States. It is the second-largest city in the state, with a population of approximately 172,622 as of 2020. Eugene is known for its outdoor recreational opportunities, including hiking and biking trails, as well as its commitment to environmental sustainability. The city is home to the University of Oregon and is often referred to as "Track Town, USA" due to its rich history in track and field athletics. Additionally, Eugene has a vibrant arts and cultural scene, with numerous theaters, galleries, and music venues.