- Dubuque is a city located in the state of Iowa, United States. It is the county seat of Dubuque County and is situated along the Mississippi River. Dubuque is the oldest city in Iowa, with a rich history dating back to its founding in 1833. The city is known for its beautiful natural surroundings, including bluffs, hills, and the river. It is also known for its historic architecture, with many well-preserved buildings from the 19th century. Dubuque is home to several colleges and universities, as well as a vibrant arts and cultural scene. The city offers a variety of recreational activities, including hiking, biking, boating, and fishing. Dubuque is also a popular tourist destination, with attractions such as the National Mississippi River Museum and Aquarium, the Fenelon Place Elevator, and the Dubuque Arboretum and Botanical Gardens.