- Cuenca is a city in the southern part of Ecuador. It is the third-largest city in the country and is located in the highlands region of the Andes Mountains. Cuenca is known for its well-preserved historic city center, which has been designated as a UNESCO World Heritage Site. The city is famous for its colonial architecture, cobblestone streets, and beautiful churches. Cuenca also has a rich cultural and artistic scene, with numerous art galleries, theaters, and museums. The city is surrounded by natural beauty, including mountains, rivers, and national parks, making it a popular destination for outdoor enthusiasts. Cuenca is also known for its traditional crafts, such as Panama hats and ceramics. Overall, the city of Cuenca offers a unique blend of history, culture, and natural beauty, making it an attractive destination for both locals and tourists.